Predicting the Next Influenza Pandemics

Avian influenza and influenza pandemics.

1 Coordinator, Risk Containment, Mapping and Drug Resistance, Communicable Diseases Surveillance and Response, World Health Organization, 1211 Geneva 27, Switzerland (email: [email protected]). Correspondence should be sent to this author. 2 Project Leader, Global Influenza Programme, Communicable Diseases Surveillance and Response, World Health Organization, Geneva, Switzerland. Ref. No. 04-012...

History of Influenza Pandemics

Influenza pandemics have been amongst the largest and the deadliest epidemics in the history of man, and were observed already in ancient times. For example, records from the fifth century B.C. suggest that influenza pandemics were observed in ancient Greece. In Europe, during the Middle Ages and the Renaissance, numerous concordant reports from different countries describe epidemics of respira...

Stockpiling Ventilators for Influenza Pandemics

Stockpiling Ventilators for Influenza Pandemics

In preparing for influenza pandemics, public health agencies stockpile critical medical resources. Determining appropriate quantities and locations for such resources can be challenging, given the considerable uncertainty in the timing and severity of future pandemics. We introduce a method for optimizing stockpiles of mechanical ventilators, which are critical for treating hospitalized influen...

Influenza Pandemics of the 20th Century

Three worldwide (pandemic) outbreaks of influenza occurred in the 20th century: in 1918, 1957, and 1968. The latter 2 were in the era of modern virology and most thoroughly characterized. All 3 have been informally identified by their presumed sites of origin as Spanish, Asian, and Hong Kong influenza, respectively. They are now known to represent 3 different antigenic subtypes of influenza A v...